Tuesday, August 13, 2019

How To Find Appropriate Literatue In PubMed










               Basic steps of literature search  

1.     Learning the steps of literature search process

2.     Understanding MeSH

3.     Determining the database searching techniques

4.     Conducting an advance search in PubMed

5.     Accessing the literature

     Essential terminologies for literature searches

ü Keyword: These are the words or phrases that researcher types in search engine/database. Keywords defines the questions/concepts we are searching about, and results are displayed accordingly. Narrower (specific) the keyword is, higher the chance of getting appropriate results. 
üMeSH (Medical subjects headings) is the national library of medicine-controlled vocabulary thesaurus, used for indexing articles for the MEDLINE/PubMed databases. Each article citation is associated with a set of MeSH terms that describes contents of citation. MeSH terms are organized in a tree with sixteen main branches such as anatomy, organisms, disease, publication characteristics and so on. Searching with MeSH is preferred over keyword searching.



           Stepwise methods of searching literature

1.     Break down the search topic into different steps:

ü Depending on types of data we are searching, keywords are also constructed accordingly.
ü Generally our search topics for experimental study results contain intervention, diagnosis and outcome keywords.
Eg: chemotherapeutic agents for breast carcinoma. Here four major keywords are used (chemotherapy, agents, breast and carcinoma)  


2.     Gathering keywords

üFor gathering keywords, Google, Google scholar and Wikipedia are used
ü Google search shows thousands of results for any keywords, including journals, official and personal websites, blogs and patient information sites. most of information by random searching are of no use. Results can be limited by directing googles algorithms to particular types of sources like site.gov, site.edu, site.org at the end of keyword.  Generally limiting .gov is preferred one to get more relevant results (governmental agencies provides data on .gov. country shortcut)
Here,  keyword 'peptic ulcer' is typed by applying two methods- random searching and specifying the algorithms. Former search showed large number of sites designed to provide  general information and later displayed only governmental sites with authentic results. 

ü Wikipedia is preferred to get background information, and references & external websites. But, content itself is not preferred in scientific communities.
ü Google scholar provides scholarly information like books, Journals articles and patents. One special characteristic of google scholars is it shows results in order that higher the article is sited for, higher will be the rank-older articles are prone to be ranked high.  
3.     Search the concepts separately in PubMed
ü Once we done with gathering keywords, we now search that particular keyword in PubMed search box.
ü Relevant MeSH terms (medical subjects headings) are searched. It’s the set of controlled vocabulary terms used by national library of medicines. In pubmed, articles are assigned in subject specialists who read over the article and determines the subjects contents. Applying MeSH term ensures that articles in same subjects are grouped together regardless of the vocabulary used by author. MeSH descriptors are arranged in a tree structure that allows to search the different level of specificity 
 Here, firstly the search icon was changed to MeSH, then keyword is typed, total of 15 major MeSH were displayed, Each  heading again contains subheadings arranged in a typical tree format. 



4.  Apply additional Database search techniques
   
I.  Truncation
ü Addition of symbol using an asterisk at the end of word stem to find variant of root word and this is very useful to find synonyms. Eg: incubat* (incubator, incubation, incubating, incubated, incubates)
II  Quotation Marks keep terms together and in order. Eg: cervical cancer metastasis contains three keywords which can be represented as one by “cervical cancer metastasis”.
III.Parentheses: allows users to combine the concepts. They are used in the same manner that are being used in mathematics equation and allows ordering the set of terms. Eg oesophageal carcinoma (adenocarcinoma).
IV.  Boolean operators
ü They are used to narrow the search and helps to find the relationship between the search terms when searching in electronic databases.
ü Three Boolean operators are AND, OR and NOT.
ü AND narrows the search by combining together two separate topics. Putting treatment And outcome Helps to find the article which contains both these concepts. Eg: child* AND “head injury”. Quotation marks is used to keep two words as a phrase and * to find the variants on this word.
ü Using OR Boolean operators broaden the search and this is often used with synonyms child* OR paediatrics OR infants* OR adolescence*.
ü Using NOT will narrow the search. It helps to remove the terms we want to exclude. Eg: childhood diarrhoea NOT rotavirus.


here, I searched for Tamsulosin and 'benign prostatic hyperplasia', by applying AND & OR. former showed 838 results where both the terms are being used, and later showed 14359 results where either of these two terms are used. 
use of NOT is dependent on knowledge & understanding of researcher.
5. Apply filter:
Filtering article according to our wish is available in pubmed, on the left hand side of the result. Applying filter reduces the number of articles significantly and increases the accuracy. 
also, literatures can be filtered by author name. After entering keyword/MeSH, authors short name in this bracket […] will show exact literature you are searching for..
                                                                    Thank You !!!


References: 










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